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Parte del entusiasmo por este nuevo agente fue la impresionante prdida de peso que demostr en el programa clnico Efecto del tratamiento con semaglutida en personas con obesidad (STEP), que respalda su aprobacin por la FDA
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Dehydration is a realistic concern because reduced appetite naturally leads to lower fluid intake
Nature 443 , 787795 (2006)
They are highly toxic to the liver and are amongst the major identified risk factors for hepatocellular carcinoma 10,11,12