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Animals were placed in a large black cube-shaped Plexiglas box with no lid that was indirectly dimly illuminated with two 40 W incandescent red-light bulbs and allowed to explore for 20 min

Your health and safety should always come first, and its important to choose treatments that are not only effective but also have a proven track record for safety

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Caution Consult your physician If you are pregnant or nursing, or have a medical condition, or taking prescription drugs, or under the age of 18 years

Editors Note: An earlier version of this story said that Lilly expects to file orforglipron to the FDA in the new year