does tirzepatide cause allodynia In four recent placebo-controlled clinical trials, dysesthesia, an unpleasant sensation that's perceived on or under the skin, was reported as a side effect of the GLP-1 agonist semaglutide in 5-23% of recipients PDF) Allodynia and Dysesthesia Associated

Request referral to appropriate specialists if needed Liver assessment : Ensure proper diagnosis through blood tests, FIB-4 calculation, and if indicated, imaging (ultrasound or FibroScan) or ELF testing Specialist review : Hepatology or endocrinology input may be needed to assess suitability Clinical trials : Some patients may be eligible for research studies examining GLP-1 agonists in NAFLD/NASH Patients should be aware that even when prescribed, GLP-1 agonists require ongoing monitoring, lifestyle modification remains essential, and treatment should be reviewed regularly to assess response and tolerability

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Druzhyna, N., Szczesny, B., Olah, G., Modis, K., Asimakopoulou, A., Pavlidou, A