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& Kelishadi, R
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Recognition of GLP-1 resistance is changing how clinicians approach obesity management
Most importantly for those living outside the country, a prescription written by a doctor in the United States is generally not valid for fulfillment at a Canadian pharmacy unless it is reviewed and co-signed by a Canadian-licensed physician
Discontinuation studies show that patients typically regain a substantial portion of lost weight within one year of stopping medication, accompanied by return of appetite and metabolic parameters toward baseline
However, broader guidance from NICE, the NHS, and the MHRA provides a clear framework for understanding how unapproved substances should be approached
