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doi: 10.1155/2020/4754195 74

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Gutzeit M, Fischer H, Nauck MA

4,5 Furthermore, the CANTOS trial (Canakinumab Antiinflammatory Thrombosis Outcome Study) revealed that anti-inflammatory treatment of cardiovascular disease with the monoclonal antibody canakinumab, targeting IL (interleukin)-1, reduces major adverse cardiovascular events by 15% compared with placebo in patients with atherosclerotic cardiovascular disease