In cortex for example, astrocytes in response to diffuse injury up-regulate GFAP and become mildly hypertrophic, however they retain their territorial domain and generally do not proliferate
GPx6 is involved in the in vitro induced capacitation and acrosome reaction in porcine sperm
Hata T, Hashimoto M, Manabe A, Aoki S, Iida K, Masumura S, Miyazaki K: Maternal and fetal nitric oxide synthesis is decreased in pregnancies with small for gestational age infants
Second, Lys105, Tyr110, Asp144 and Glu147 all stick out on the protein surface, are on top of the scaffold site and form a protein area in a 120 angle to the glutathione-scaffold site (Fig
So, deficiency symptoms may also include depression, cognitive issues, difficulty balancing, and tingling in the appendages all nerve and/or brain related
Again, it's not to discount completely that the GI side effects may play a role, but I would say that, if anything, they may be more contributing to