If we start covering every off-label use based on Reddit testimonials and mechanistic hand-waving, costs become unsustainable, and we incentivize medical anything-goes behavior
Tsuzi, D., Maeta, K., Takatsume, Y., Izawa, S
Semaglutide is a groundbreaking GLP-1 medication used primarily for weight loss and managing blood sugar levels
Unlike Ozempic, however, which targets only the GLP-1 receptor, tirzepatide activates both the GLP-1 and GIP receptors
In order to investigate this, they started the SURMOUNT-4 study, which ran from March 2021 to May 2023 at 70 sites in Argentina, Brazil, Taiwan, and the United States