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Guan AY, Chen Y, Tseng SC, Lin Q

Saldeen, P., & Saldeen, T

Excessive ROS damages nucleic acids, proteins, and lipids to induce cell death, and sufficient intracellular GSH is critical for ROS clearance and cellular homeostasis [24,25,26,27,28,29,30]

Moreover, other specialized mitochondria-residing proteins, such as the apoptosis inducing factor (AIF) and endonuclease G, are translocated to the nuclei following their release from mitochondria and promote peripheral chromatin condensation and high molecular weight DNA fragmentation

A randomized phase II study of PX-12, an inhibitor of thioredoxin in patients with advanced cancer of the pancreas following progression after a gemcitabine-containing combination

Weijl NI, Elsendoorn TJ, Lentjes EG, Hopman GD, Wipkink-Bakker A, Zwinderman AH,