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These findings were published in JAMA Psychiatry

Approximately 20% of CRC patients will develop metastases, resulting in a less than 5-year survival rate of only 14% with conventional treatment (Rumpold et al., 2020)

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It achieves this by precisely activating ghrelin (GHS-R1a) receptor pathways without significantly elevating other pituitary hormones, such as cortisol or prolactin, in experimental models

This dual approach, direct ROS scavenging through electron donation and indirect antioxidant enhancement via Nrf2 activation, explains ESCs effectiveness in various cases of oxidative stress-related diseases (Jayakumar et al

doi: 10.1126/science.1241165 90 SpaggiariG.BriganteG.De VincentisS.CattiniU.RoliL.De SantisM