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A 2016 study published in Nature Scientific Reports showed that GHK-Cu had no cytotoxicity to human keratinocytes at concentrations up to 5,800 micromolar over 72 hours and did not induce inflammatory biomarkers

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I'll start with the fact that I have very sensitive skin, most ingredients irritate me

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These metabolites may indirectly influence lipid peroxidation through their involvement in antioxidant defense or signal transduction pathways (Figure 13)

Metabolite identification using infrared ion spectroscopyNovel biomarkers for pyridoxine-dependent epilepsy