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I think that probably the predominant factor that will drive changes in life expectancy over the next 5 to 10 years will be better treatment of obesity with GLP-1 receptor agonists and related agents. Given the potentially huge health benefits of these diabetes and weight loss drugs, should insurers and government programs such as Medicaid widely cover their use

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The published preclinical melanogenesis literature for MT-II is well-developed and reproducible across frog (Rana pipiens), lizard (Anolis carolinensis), and mammalian skin bioassays, where the cyclic peptide was reported as approximately 90-100 more potent than native -MSH [2]

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The longevity story is a reframe, not a verdict