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While these early improvements are encouraging, the more visible results related to deep tissue repair and collagen rebuilding typically take about eight to twelve weeks to fully appear

10.3390/antiox9111146 Antioxidants

One way UV light speeds up aging is by enhancing free radical production

In a comparative study the size dependency of BBB uptake and permeability was investigated for nanoparticles from 50 to 500 nm of various composition (polystryrene, protein, lipid) on a human culture BBB model in which transferrin nanocarriers with 500 nm diameter showed the most successful BBB penetration [61]

The best results come with time, consistency, and a healthy routine

For formulation studies, consult licensed professionals and published protocols