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Furthermore, iron-regulatory proteins (IRPs), comprising IRP1and IRP2, regulated the expression of TF, TFR1, DMT1, and FPN1 by binding to a stem-loop structure located in the 3- or 5-untranslated region of the target mRNA for stabilization (Wang and Pantopoulos, 2011)
Anticonvulsant activity of Benkara malabarica (Linn.) root extract: in vitro and in vivo investigation
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Their primary mechanisms of action include: Enhancing glucose-dependent insulin secretion from pancreatic beta cells Suppressing glucagon release , which reduces hepatic glucose production Slowing gastric emptying , leading to prolonged satiety Acting on appetite centres in the brain to reduce food intake These combined effects result in improved glycaemic control, reduced HbA1c levels, and significant weight loss in many patients
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