Harvard Toshniwal Paharia, Pooja Toshniwal Paharia
Compounded GLP-1 medications are not FDA-approved finished products
A lysine at position 28 is switched out for an arginine, which leaves another lysine at position 26 free to be modified with a long fatty-acid/ethylene glyol-like chain, which improves the drugs half-life in the blood even more (by binding to serum albumin)
First, safety and adherence should always come first
This is unlike fat soluble vitamins, like vitamins A, D E, and K, which will continue to get stored in the bodys fat when supplemented excessively, and can lead to side effects if over supplemented beyond the bodys needs
Understanding their effect and safety based on their unregulated injectable form is important