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Patients will need to be on each dose level for one month before theyre able to get a higher dose

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Initially, claims centered around severe nausea, gastroparesis, and intestinal blockages

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A separate study (Copinschi et al., Neuroendocrinology, 1997, N=8) demonstrated that MK-677 increased Stage IV (deep) sleep duration by 50% and REM sleep by 20%, improvements that were sustained throughout the 2-week study period