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Serious adverse effects are rare but have been reported, particularly with IV administration of thiamine

It is a synthetic fragment of human growth hormone (amino acids 176-191), studied in research settings for its proposed role in fat metabolism

Key findings of the paper: Finding 1: NNMT is highly expressed in adipose tissue

Under refrigerated storage at 28C and protected from light and freeze-thaw cycles, reconstituted solution is generally used within four weeks

No validated human dose, half-life or safety programme was identified

Whilst many symptoms improve with appropriate B12 treatment, not all resolve completely, especially if neurological damage was severe or prolonged before treatment commenced