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Some studies have reported that depression caused by chronic stress disrupts the BDNFtropomyosin related kinase B (TrkB) receptor signaling pathway in the PFC and hippocampus, and ultimately contributes to impaired synaptic maturation, synaptic protein synthesis, and glutamate receptor cycling (Duric et al., 2010
Tricyclic antidepressants (TCAs) Amitriptyline and nortriptyline: Effective in managing PDPN by inhibiting monoamine reuptake and blocking sodium channels
Brain Topography 14 : 131137
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However, its still essential to maintain balanced meals with enough nutrients
It is a health risk
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