Glucagon-like peptide-1 causes pancreatic duodenal homeobox-1 protein translocation from the cytoplasm to the nucleus of pancreatic beta-cells by a cyclic adenosine monophosphate/protein kinase A-dependent mechanism
Residual beta-cell function more than glycemic control determines abnormalities of the insulin-like growth factor system in type 1 diabetes
Based on these data, we speculated that T3 might have an insulinotropic effect, which contributed to its glucose-lowering action
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Randomized controlled trials are underway, regulatory decisions lie ahead, and real-world data will continue to accumulate
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