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Abstract Acute high-altitude illness (AHAI), triggered by hypobaric hypoxia following rapid ascent to high elevations, induces complex pathophysiological responses that may be life-threatening

These modifications are discussed in research literature for their effect on reducing binding affinity to insulin-like growth factor binding proteins, resulting in extended biological half-life in experimental models

it typically occurs in combination with deficiencies of other water-soluble vitamins

Consult with a health care professional to ensure safety and efficacy based on your health profile and expectations

Patel, S

PMCID: PMC3770294