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It is mainly responsible for transporting neutral and basic amino acids, but not acidic amino acids (e.g., aspartic acid and glutamate)
Increased HIF-1 activity stimulates ASCT2 transcription alongside other amino acid transporters to boost glutamine uptake which supports cell survival and proliferation within hypoxic tumor settings
Chem Biol Interact (2006) 160(1):140
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In a small RDP study, the effects of Pycnogenol on gulf war illness were investigated
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