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It may also be important to monitor levels of certain vitamins and minerals

The Particle-mesh Ewald (PME) method was utilized to handle electrostatic interactions

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For severe gastrointestinal losses, temporarily holding the medication and ensuring adequate hydration may be necessary to prevent acute kidney injury

Population pharmacokinetic analysis showed that the apparent oral clearance of empagliflozin decreased with a decrease in eGFR leading to an increase in drug exposure