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Adems, las neuronas del NTS, que recogen aferencias de origen perifrico, sintetizan pre-proglucagn y son fuente de GLP-1 en el propio SNC, que alcanza mediante vas neuronales receptores especficos localizados en estructuras clave en el control de la ingesta, como el ncleo paraventricular, el septo lateral, el ncleo accumbens y el ncleo parabraquial lateral2,3,6