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Rosano GMC, Tamargo J, Kjeldsen KP, Lainscak M, Agewall S, Anker SD, et al

Common Side Effects Usually improves over 2-4 weeks as your body adjusts Can be managed with dietary adjustments Typically mild and temporary Increase fiber and water intake Reduced appetite is the intended therapeutic effect Usually mild and improves over time Thyroid tumors (C-cell carcinoma)- Boxed warning Avoid if you have family history of medullary thyroid cancer or MEN 2 syndrome Pancreatitis- Rare but serious Seek immediate care for severe, persistent abdominal pain Gallbladder disease- Monitor for symptoms Report upper right abdominal pain, especially after meals Kidney problems- Risk increases with dehydration Stay well hydrated throughout treatment Severe allergic reactions- Rare Seek emergency care for breathing difficulty or severe swelling Tips for Managing Side Effects Start with the lowest dose and increase gradually as directed Eat smaller, more frequent meals instead of large ones Avoid high-fat, greasy, or spicy foods that may worsen nausea Stay well hydrated - drink plenty of water throughout the day Report persistent or severe side effects to your healthcare provider What should I know about Semaglutide

The plated cells were treated with cell lysis buffer and scraped, and following centrifugation the lysates were stored at 20 o C pending analysis

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