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Blood pressure typically decreases 4-6 mmHg with GLP-1 treatment

However, patients with complex arrhythmias or advanced heart failure should be monitored more closely

By combining these two, researchers observe a dual-vector effect: higher peak secretion and sustained elevation, without the hunger side effects of GHRP-6 or the cortisol spikes of GHRP-2

However, its metabolism places a significant burden on the livers detoxification and antioxidant systems , particularly through depletion of glutathione

Similarly, newer GLP-1 and GIP medications used for weight management and metabolic health require careful dosing, monitoring, and follow-up to ensure both effectiveness and safety over time

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