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Skipping protein: Without enough protein, your body may break down muscle instead of fat, slowing metabolism and making it harder to sustain progress
J.LealJ.GrayA
Insurers raised cost-sharing sharply for GLP-1s in recent years, Klebanoff found
In liver disease, semaglutide received FDA accelerated approval in August 2025 for metabolic dysfunction-associated steatohepatitis in adults with moderate-to-advanced fibrosis
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Knowing how long semaglutide takes to work helps set expectations for when these initial adjustments resolve
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