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Compared with controls, the researchers observed: Fewer beneficial gut bacteria involved in breaking down dietary fiber Lower levels of short-chain fatty acids, compounds that help support the gut lining and play a role in inflammation control Higher levels of inflammatory markers in the blood Increased liver weight, which can be consistent with low-grade inflammation A smaller cecum the part of the intestine where gut bacteria break down fiber and produce protective compounds Reduced levels of a brain-derived protein associated with cognitive impairment Taken together, the results suggest SNAC may influence the gut ecosystem and inflammation-related pathways, not just medication absorption
Ethics declarations Conflict of Interest Makoto Ohara has received lecture fees from Eli Lilly Japan K.K
We performed a students paired t-test to determine statistically significant changes in the levels of the components of metabolic syndrome, lipid panel, hepatic panel, and adiposity, oxidative stress, and inflammation biomarkers measured at the end of 4th week during 4-week intermittent fasting, and 1 week after 4-week intermittent fasting
(1990) 4(Suppl 4):8539
