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2.2 Animals Thirty-two male BALB/c mice, aged 68 weeks and weighing 1822 g, were provided by Jinan Pengyue Experimental Animal Breeding Co., Ltd

Thus, if a patient were in Stage 3a based on their GFR, but had normal excretion of protein in their urine and no other indications of kidney disease, that would warrant continued monitoring of that patient for changes, but not necessarily aggressive therapy for CKD [24]

World Health Organization (WHO) estimates indicate that among individuals older than 60 years, osteoarthritis prevalence reaches approximately 10% in men and 18% in women

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