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The label expansion was supported by two Phase III trialsa 12-week induction study and a 52-week maintenance studyboth of which met the primary endpoint of clinical remission

That extended duration is why a once-weekly injection works

While individual variation exists with any medication, this pattern warrants attention given the FDA concerns about compounded product consistency

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Our study demonstrated the effectiveness of UA in enhancing the expression and activity of GPX4, as evidenced by western blot and RT-PCR results