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Existing weight-loss drugs such as Wegovy, commonly referred to a GLP-1s, mimic the effects of glucagon-like peptide-1, a hormone that regulates metabolism

doi:10.1016/j.xops.2023.100341 31

However, depending on gut microbiota composition, the risk of having an adverse cardiovascular event may be lower in individuals with low versus high circulating TMAO even though choline and/or betaine concentrations in the blood are elevated (115)

GLP-1 medications may cause nausea, injection site reactions, and rare pancreatitis

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