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Unlike prior weight-loss medications that act on one or two incretin pathways, retatrutide stimulates three , resulting in: Significant reductions in appetite Enhanced energy expenditure Dramatic improvements in metabolic markers Some of the largest weight-loss percentages ever observed in a clinical trial The enthusiasm is justified

doi: 10.1161/circulationaha.107.735795 15 JensterleMRizzoMHaluzkMJaneA

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