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And so the drug that we ultimately came up with was metformin
GLP-1 works in several important ways
Confirmatory secondary endpoints showed an 18% reduction in the risk of composite heart failure events (including cardiovascular death, heart failure emergency visits, and hospitalization) compared to placebo (HR: 0.82
however, during the initial phases of both type 1 and type 2 diabetes, there is an increase in renal size accompanied by an increase in GFR due to hyperfiltration [24,25,26]
Basyal, B., Jariwala, S., Shrestha, P., Busa, G., Sel, K., & Doshi, S
Direct Stimulation of GLP-1 Receptors in the Brain: GLP-1 receptors are found in various areas of the brain, particularly those involved in appetite control and the sensation of nausea
