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In a case series of 49 patients, the mean age was 51.2 years and the most common sites involved were the trunk, the head and neck, the extremities, and the acral areas [23]

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doi: 10.2337/diabetes.47.5.764 39 PaulyRPDemuthHURoscheFSchmidtJWhiteHALynnFet al

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However, tirzepatide's glucose-dependent mechanism of action means that hypoglycemia risk is low when used as monotherapy or with metformin

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