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Kluijtmans LAJ, Boers GHJ, Stevens EMB, Renier WO, Kraus JP, Trijbels FJM, van den Heuvel LPWJ, Blom HJ: Defective cystathionine beta-synthase regulation by S-adenosyl-methionine in a partially pyridoxine responsive homocysteinuria patient

S., Lee, C

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The severe deficiency of this enzyme results in a reduction of the NADPH generation, which results in a decrease in the production of hydrogen peroxide (H 2 O 2 ) and therefore the neutrophil microbicide activity is affected and likewise its inflammatory response 16

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The conical bottom allows for the easy settlement of the fluff