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In addition to its role in energy production via the TCA cycle, -KG plays a central role in amino acid synthesis, redox balance, and the regulation of cell signaling

4(4): p.193-202

Its targeted mechanism makes it relevant in studies focused on weight management and metabolic health

On the other hand, the chronic OS will produce an excessive accumulation of ROS, which in turn induces the production of damage-associated molecular patterns (DAMPs) and the release of melanosomal antigens that activate innate immunity (41)

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They examine its role in cell migration, cytoskeletal organization, and extracellular matrix remodeling