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Longitudinal effects of aging on serum total and free testosterone levels in healthy men
GLP-1 RAs not only ameliorate insulin resistance and microvascular injury [84], which are significant determinants of depression in T2DM, but also enhance dopamine metabolism and stimulate growth factor signaling pathways, suggesting potential neuroprotective functions [85,86]
Data were processed using GraphPad Prism 8 software (GraphPad software Inc., San Diego, CA, USA), and differences between groups were analyzed by unpaired Students t test or one-way analysis of variance (ANOVA)
The datasets were combined for analysis
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