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Thus, unlike previous in vitro biochemical studies or metabolic engineering efforts, which had excluded arGSTs, we set out to confirm our hypothesis by performing coupled enzymatic reactions with 3,4- cis -leucocyanidin ( 6 ) combining clarified Escherichia coli cell lysates expressing At LDOX and the well-studied arGST Ph AN9 from petunia

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engineered a UV crosslinked GelMA spherical hydrogel (W-Exo-L@GelMA) that encapsulated engineered exosomes modified with the chondro affinity peptide WYRGRL and the anti-inflammatory inhibitor LRRK2-IN-1

These are generally mild to moderate and dose-related