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Notably, recent evidence from a comprehensive review highlights that GLP-1RAs promote myelinogenesis and myelin maintenance, with their beneficial effects potentially mediated through PI3K/AKT pathway activation [263]
The pivotal Phase 2 trial (NCT04881760), published in The New England Journal of Medicine (Jastreboff et al., 2023), enrolled 338 adults with BMI 30 or higher
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The Never Rule: Never freeze these medications
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Just make sure youre not mixing it with calorie-dense drinkslike flavoured milks, syrups, or sweet lattesif you're being mindful of your weight
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