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DOI: 10.1148/55.6.865 4

Only 4.2% discontinued due to side effects after week 24

This shift in bacterial composition can change gas production patterns, alter the types of short-chain fatty acids being produced, and modify how your gut processes different foods

Tirzepatide combines GIP and GLP-1 activation Mazdutide combines Glucagon and GLP-1 activation Both reduce appetite and support weight loss but their secondary pathways give each drug a unique profile especially in areas like energy expenditure , liver fat reduction , and blood sugar improvement

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