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The initial model was rigid-body fitted into the consensus EM density map via UCSF Chimera 1.14 32 , followed by manual adjustment using ISOLDE 33 embedded in UCSF ChimeraX 1.6 34
ACS Chemical Biology, 16 (8), 13181324
Tirzepatide is a dual-action medication known as a GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) receptor agonist
Skeletal muscle is the bodys main sink for glucose after meals
Its the sensation that you or your surroundings are spinning or tilting, even when youre standing still
Nature 542 , 119123 (2017)
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