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Common side effects include nausea, vomiting, diarrhea, and constipation, which often subside as the body adjusts to the medication
Other antioxidant enzymes, including GCH1 (GTP cyclohydrolase 1) [136], NOS2/iNOS (nitric oxide synthase 2) [137], MGST1 (microsomal glutathione S-transferase 1) [138], GSTZ1/maleylacetoacetate isomerase (glutathione S-transferase zeta 1), TXNRD1 (thioredoxin reductase 1) [139], PLA2G6/iPLA2/PNPLA9 (phospholipase A2 group VI) [16, 17], and peroxiredoxins (PRDX) [140], also inhibit ferroptosis in a context-dependent manner, even in GPX4 - or AIFM2 -knockout cancer cells
That point reinforces a documentation-first approach for RUO materials
Washington (DC): National Academies Press (US) (2000) Food And Nutrition Board, Institute of Medicine-National Academy of Sciences Dietary Reference Intakes: Recommended Intakes for Individuals
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