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[38] At the time of suspension, the trial was criticized for other methodological flaws, including being conducted by "fringe" clinicians, and lacking prior Phase I and II studies
Husain and colleagues reported cardiovascular-outcome data for the oral formulation in the PIONEER 6 trial [6]
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But a large percentage of them are false negatives which in many cases prevents prompt diagnosis and treatment resulting in more hospitalizations/need for ICU care/or even death
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