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In the PWA model, GE suppressed hypothalamic expression of BCAP31, a pro-apoptotic protein, and promoted proteins associated with autophagy-critical processes for neuronal function and energy homeostasis

Estos frmacos han demostrado no solo ser efectivos en la reduccin del peso corporal, sino que tambin han mostrado beneficios adicionales sobre diversas enfermedades asociadas a la obesidad que afectan de manera muy prevalente a las personas que conviven con obesidad (fig

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Furthermore, patients report that substance cravings fully return with cessation of treatment and disappear again when treatment is resumed