doi:10.5935/1518-0557.20190033 Pooyandjoo M, Nouhi M, Shab-Bidar S, Djafarian K, Olyaeemanesh A
In each step, unconventional reaction conditions are imposed, such as carbonyl dimethylacetone (DCC) and N,N-dimethylamine (DMAP), and strong acids such as trifluoroacetic acid are used to remove the protecting groups
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Treatment strategies remain limited, focusing on symptomatic management, neuroprotective interventions, and behavioral therapies
Such patients may be less optimal candidates for invasive surgical procedures due to perioperative risks, recovery potential, and contraindications linked to advanced frailty or polypharmacy
However, the best results are usually seen when combined with proper nutrition, calorie control, cardio, and consistent exercise