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10 Conclusion Pancreatogenic diabetes remains under-recognised, frequently misclassified, and clinically underserved despite its substantial impact on morbidity and mortality

For functional enrichment analysis, enriched gene sets were determined by applying the same workflow used for RNA, using the R package gprofiler2 (v.0.2.0)

For GIPR antagonist activity, HEK293T cells stably expressing human GIPR were used to measure peptide or peptideantibody conjugate-induced cAMP production in a homogenous time-resolved fluorescence assay (Cisbio, cat

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7 Recent data shows that GIP is responsible for a substantial portion of postprandial insulin secretion in T2DM and mild hyperglycemia in early disease