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On the basis of these findings, researchers are calling for evidence-based discontinuation protocols for GLP-1 therapies, which have taken the world by storm in recent years

The authors found that semaglutide was associated with certain adverse events more often

As your dose increases, side effects may temporarily return

10.1016/j.ejphar.2017.07.015 137

Notably, several regions in the reward system co-express receptors for neurotransmitters and neuropeptides, allowing metabolic state to directly influence neural signaling (e.g., dopamine, acetylcholine