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The semaglutide weight loss injections work by affecting the hormones in your body that regulate hunger and fullness
Hospital-backed health systems are expanding GLP-1 use to treat chronic kidney disease, cardiovascular complications, and non-alcoholic steatohepatitis (NASH), as per Morgan Stanley
The mechanism is well-established
In the subset of patients who had creatinine measurements available, we calculated estimated glomerular filtration rate using the race-free 2021 CKD-EPI (chronic kidney disease epidemiology collaboration) equation.32 Statistical analysis To adjust for confounding, we used 1:1 propensity score matching with the nearest neighbor method and a caliper of 0.01 of the propensity score.33 We used multivariable logistic regression models to estimate the propensity scores
Still, the clear pattern seen with Wegovy and the higher risk in males suggests that doctors should monitor patients carefully, especially those receiving the higher doses for obesity
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