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doi:10.1038/clpt.2010.184 Lyssenko V, Lupi R, Marchetti P et al (2007) Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes

First of all, they report asking the women not to make any lifestyle changes during the course of the study

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Thus, to deal with their growing use, different reimbursement policies are also being introduced by the government