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Translational readthrough agents, such as Geniticin and ELX- 02, which allow translational readthrough of premature stop codons in mRNA to produce the full-length protein, have been explored for CTNS missense mutations

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The researchers noted that compared with the control group, the epithalamin-treated patients exhibited [10]: Decelerated aging of the cardiovascular system Decreased rate of cardiovascular mortality and cardiovascular failure (-50%) Less age-associated impairment of physical endurance Normalized circadian rhythm for melatonin production Normalized circadian rhythm for lipid (fats) and carbohydrate metabolism Lower rate of mortality (-28%) The follow-up study on long-term epithalamin treatment represents strong evidence of eptithalons favorable safety profile and relative absence of notable epithalon side effects