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On the other hand, the sulfhydryl-reacting compounds such as acetaldehyde decrease the transepithelial resistance (TER) through a covalent modification of cysteine residue Cys215 of the protein tyrosine phosphatase and this toxicity can lead to damage in the intestinal cells that eventually may lead to intestinal and stomach cancer (198) and this evidence can be used to hypothesize and indicate the involvement of patulin in the development of intestinal and stomach cancer in humans

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Jellinger KA (2020) Neuropathological assessment of the Alzheimer spectrum

Folate, vitamin B12, one carbon metabolism and the nervous system: Excess folic acid is potentially harmful

Heavy metal neurotoxicants induce ALS-linked TDP-43 pathology