Hepatology 21(6):16101617 Nagai H, Matsumaru K, Feng G, Kaplowitz N (2002) Reduced glutathione depletion causes necrosis and sensitization to tumor necrosis factor-alpha-induced apoptosis in cultured mouse hepatocytes
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GOx, as an enzyme catalyst which catalyzed the conversion of glucose into H 2 O 2 , can produce starvation effect on tumor cells as well as provide raw materials for Fenton-like reactions